After graduating with a degree in Zoology from Cambridge University, Colin Bertram took part in several scientific expeditions, including a trip to East Greenland and a nine-month study of coral reefs in the Red Sea.
In 1934, Bertram agreed to work as a biologist on a three-year expedition to Graham Land. Despite initially working as a marine biologist on this trip, Bertram switched roles to become a shore biologist. As part of this new role, Bertram travelled over 600 miles by dog sled and helped to discover the George VI Sound, an ice-filled bay that separates Alexander Island from the Antarctic Peninsula. The Betram Glacier which flows into the George VI Sound is named after him.
During the Second World War, Bertram worked with the Scott Polar Research Institute to design and test Arctic clothing and equipment for the Army. His research here led to the invention of the string vest which is designed to minimise heat loss by allowing a thin layer of air to circulate next to the skin. Bertram also spent three years in Palestine as Chief Fisheries Officer and helping to organise food resources in the region.